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GLP-1 Program · Pillar Three

Weight loss shouldn't
cost you your hair.

Hair loss is one of the most distressing and least discussed side effects of GLP-1 therapy. It's common, it's real, and it's treatable — but only if it's addressed early and directly. At Le Sommet, we treat it with scalp microneedling and Platelet-Rich Plasma: the most clinically supported non-pharmaceutical intervention available.

What's Happening

Why GLP-1 Medications Cause Hair Loss

The hair loss most GLP-1 patients experience is called telogen effluvium — not a direct effect of the medication itself, but a response to the physiological stress of rapid weight loss and significant caloric restriction. When the body experiences sudden metabolic change, it reallocates resources away from non-essential functions. Hair growth is one of the first things deprioritized.

In telogen effluvium, hair follicles shift prematurely from the active growth phase (anagen) to the resting phase (telogen). The hair doesn't fall out immediately — it falls out 2–4 months later when the resting follicles shed. This is why patients often don't notice the hair loss until they're several months into their GLP-1 program and the weight loss is well underway.

The good news: telogen effluvium from weight loss is not permanent hair loss. The follicles are resting, not dead. With the right intervention — particularly one that restores blood supply, growth factor signaling, and follicle activity at the scalp level — regrowth is achievable. The key is treating it before the resting phase extends so long that follicle health is compromised.

How It Unfolds
Month 1–2
GLP-1 therapy begins, caloric restriction increases

Appetite suppression reduces intake significantly. Hair follicles begin receiving fewer nutrients and metabolic resources. The shift toward telogen phase begins at the follicle level — invisibly.

Month 3–4
Follicles in resting phase; no visible change yet

Hair that has shifted to telogen continues to anchor in the scalp. Patients often feel good — weight is coming off, energy is improving. Hair loss has not yet appeared.

Month 4–6
Shedding begins — often alarming in volume

Resting hairs shed, sometimes in significantly higher-than-normal volume. Many patients notice it in the shower, on their pillow, or in their brush. This is when most people become concerned.

Month 6+
Ideal treatment window — follicles still viable

This is when we want to intervene. Follicles are in telogen but not yet miniaturized. Scalp microneedling + PRP can restimulate the growth cycle and support regrowth before any permanent changes occur.

How We Treat It

Scalp Microneedling + PRP: The Most Supported Approach

The combination of scalp microneedling and Platelet-Rich Plasma represents the strongest evidence-based non-pharmaceutical approach to hair loss treatment — and it works by addressing the follicle directly where the problem originates.

Step One
Scalp Microneedling

SkinPen® creates thousands of controlled micro-channels in the scalp, triggering a localised healing response that increases blood flow to the follicle bed, stimulates collagen and growth factor production, and — critically — creates direct pathways for PRP to penetrate to the follicle level. The scalp's intact barrier normally prevents topical treatments from reaching the follicle at therapeutic depth. Microneedling removes that barrier temporarily, transforming the delivery of everything applied afterward.

Step Two
Platelet-Rich Plasma (PRP)

PRP is produced from a small sample of your own blood, centrifuged to concentrate platelets at 5–10× normal levels. These platelets release growth factors — PDGF, TGF-β, VEGF, and others — that directly signal hair follicles to move from the resting phase back into the active growth phase. Applied immediately after scalp microneedling while the channels are open, the PRP reaches the follicle at therapeutic depth rather than sitting on the surface. Because it's autologous — from your own blood — there is essentially no risk of allergic reaction.

Why Together
The channels make
the PRP work.
The PRP makes the
channels matter.

Neither treatment alone produces what the combination achieves. Scalp microneedling without PRP provides follicle stimulation and improved blood flow — meaningful, but limited. PRP applied to an intact scalp sits on the surface and cannot reach the follicle at depth. Together, the microneedling creates the pathway and the biological signal; the PRP delivers the growth factors directly to where the follicle can respond to them. This is why the combination has significantly stronger clinical evidence for hair regrowth than either intervention alone.

01
Blood draw & PRP preparation

A small blood sample is drawn and centrifuged while you receive a topical numbing agent. PRP is ready to apply within 10–15 minutes.

02
Scalp microneedling

SkinPen® passes across the affected scalp areas with precise depth control — creating thousands of micro-channels that stimulate the follicle bed and open pathways for PRP delivery.

03
PRP application into open channels

PRP is applied immediately while the channels are open — penetrating to the follicle level and beginning the growth factor signaling process that supports the shift from telogen back to anagen phase.

04
Series of 3–4 sessions, 4–6 weeks apart

Most patients require a series of treatments. Regrowth typically becomes visible 3–6 months after the first session as the follicle cycle restarts.

Questions

Common Questions

Is the hair loss permanent?+
Telogen effluvium caused by weight loss is not permanent hair loss in the way that androgenetic alopecia is. The follicles are resting, not permanently miniaturized or destroyed. In most cases, the shedding phase resolves on its own within 6–12 months — particularly as weight stabilizes and nutrition improves. Scalp microneedling with PRP accelerates this recovery and can support more complete regrowth compared to waiting it out. It is most effective when begun during active shedding, before the resting phase extends long enough to compromise follicle health. If you have a personal history of androgenetic alopecia, GLP-1 therapy can sometimes accelerate that process — which we discuss at your consultation.
When should I start treatment?+
Earlier is better. For patients at higher risk — those losing weight rapidly, with a history of hair loss, or with nutritional deficiencies — we recommend beginning scalp treatment proactively, even before shedding appears. For patients who have already noticed increased shedding, the window for effective intervention is still open — and we start immediately. Treatment begun during active shedding consistently produces better outcomes than waiting until the shedding resolves on its own.
How many sessions will I need?+
Most patients complete a series of 3–4 scalp microneedling + PRP sessions spaced 4–6 weeks apart. Visible regrowth typically begins 3–6 months after the first session, as the follicle cycle takes time to restart. Patients who remain on GLP-1 therapy during treatment may need maintenance sessions as the underlying caloric restriction continues to create some follicle stress. We assess your response after each session and adjust the treatment plan accordingly.

Protect your hair
from the start.

Hair loss treatment is most effective when it begins early. Don't wait for the shedding to become alarming — address it as part of a complete GLP-1 program.

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