GLP-1 Program · Pillar Two

The weight comes off.
Your muscle stays.

GLP-1 medications produce powerful weight loss — but without active intervention, a significant portion of that weight comes from lean muscle mass rather than fat. This is the most underaddressed consequence of GLP-1 therapy. We address it directly.

Join the Program ← Back to Full Program

Why This Matters

The Muscle Loss Problem Nobody Talks About

When the body loses weight rapidly — as it does on GLP-1 medications — it does not selectively burn fat. Research consistently shows that 25–40% of total weight lost during GLP-1 therapy can come from lean muscle mass, particularly when caloric intake drops without adequate protein and resistance stimulus to signal the body to preserve muscle tissue.

This matters enormously beyond how you look. Muscle mass drives your resting metabolic rate — the number of calories your body burns at rest. When you lose muscle, your metabolism slows. Strength, joint stability, balance, and fall risk are all directly tied to the muscle you carry. And critically: lost muscle does not return on its own when medication is discontinued, which is one of the primary mechanisms behind weight regain after GLP-1 therapy ends.

The solution is active intervention — not hoping adequate protein and exercise will compensate, but directly stimulating and rebuilding muscle at clinical depth while ensuring the body has the nutrients it needs to protect what it has.

The Research

25–40% Of total weight lost on GLP-1 medications can come from lean muscle mass without active intervention to preserve it

~20,000 Supramaximal muscle contractions delivered per EMSCULPT NEO® session — more than any voluntary exercise can produce

25% Average increase in targeted muscle mass in clinical studies of EMSCULPT NEO® across a standard 4-session series

0 Minimum caloric burn or physical exertion required — making EMSCULPT NEO® available even when exercise capacity is limited

How We Treat It

Two Interventions. One Comprehensive Strategy.

Muscle preservation during GLP-1 therapy requires both a direct stimulus to the muscle and the nutritional raw materials the body needs to respond to that stimulus.

Direct Muscle Stimulation

EMSCULPT NEO®

EMSCULPT NEO® uses High Intensity Focused Electromagnetic technology to deliver supramaximal contractions directly to targeted muscle groups — bypassing the need for voluntary exercise and producing a stimulus the body cannot replicate on its own. Sessions run 30 minutes per area. We typically target the core and lower body for GLP-1 patients, as these are the muscle groups most critical to metabolic function, strength, and long-term weight maintenance. EMSCULPT NEO® can build and preserve muscle even in patients whose caloric restriction, fatigue, or GLP-1-related GI effects make regular exercise difficult.

Full EMSCULPT NEO® page →

Nutritional Foundation

IV Nutrition Therapy

GLP-1 medications dramatically reduce appetite and slow gastric emptying — making it genuinely difficult to consume adequate protein, vitamins, and minerals through food alone, even when you're trying. IV nutrition bypasses the GI system entirely, delivering nutrients directly into the bloodstream where they can be immediately utilised. We formulate drips specifically for GLP-1 patients: protein-supporting amino acids, B vitamins for energy metabolism, magnesium, and the micronutrients that muscle synthesis and hair health both depend on. Monthly IV sessions during active GLP-1 therapy significantly reduce the deficiency-driven side effects that contribute to both muscle loss and hair loss.

Full IV Therapy page →

Questions

Common Questions

Can I do EMSCULPT NEO® while I'm actively losing weight on a GLP-1?+

Yes — and this is actually the ideal time to do it. Running EMSCULPT NEO® concurrently with your GLP-1 weight loss phase is more effective than waiting until weight loss plateaus, because you're preserving and building muscle at the same time the medication is changing your caloric environment. The muscle you build now becomes the metabolic asset that protects your results after the medication ends. We coordinate the session cadence with your GLP-1 titration schedule to optimise timing.

Which areas does EMSCULPT NEO® target in the GLP-1 program?+

For most GLP-1 patients, we prioritize the abdomen and core, glutes, and quadriceps — the muscle groups most important to metabolic rate, mobility, and long-term weight maintenance. Patients with specific concerns or post-surgical deficits may have additional areas incorporated. We determine the treatment plan at your consultation based on your baseline strength, your goals, and your overall program structure.

How often do I need IV nutrition during a GLP-1 program?+

For most patients in active weight loss, monthly IV sessions provide meaningful nutritional support. Patients whose appetite suppression is more significant, or whose labs show notable deficiencies, may benefit from more frequent sessions during the early titration phase. We review labs at regular intervals and adjust the frequency of IV nutrition accordingly — this is not a one-size recommendation.

Lose fat.
Keep your strength.

Muscle preservation is built into every Le Sommet GLP-1 program from day one — not added after the loss is already done.

Join the GLP-1 Program View Full Program

Continue exploring

All treatments and concerns · Patient resources · Book a visit

The weight comes off. Your muscle stays.